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鍞悗鏈嶅嫏(w霉)
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宸︽礇寰�(f霉)鐨勫姂閲忚(di脿o)鏁达細灏�(du矛)浜庢瘡鏃ユ湇鐢�1鐗囷紙50mg锛夌檪鏁堜笉浣宠€屽皪(du矛)钘ョ墿鑰愬彈鎬ц純濂界殑鎮ｈ€呭彲澧炲姞鍔戦噺锛屽洜鑸嶆洸鏋楃殑娑堥櫎鍗婅“鏈熺偤24灏忔檪(sh铆)锛岃(di脿o)鏁村姂閲忕殑鏅�(sh铆)闁撻枔闅斾笉鎳�(y墨ng)鐭簬1鍛�锛屾渶澶у姂閲忕偤4鐗囷紙200mg锛�/鏃ャ€傚姂閲忕殑瑾�(di脿o)鏁存槸闇€瑕佸湪閱�(y墨)鐢熺殑鎸囧皫(d菐o)涓嬮€�(j矛n)琛岀殑锛岃€屾偅鑰呬篃鎳�(y墨ng)瑭茬洝鍙兘閰嶅悎閱�(y墨)鐢熺殑娌荤檪宸ヤ綔锛屾寜鐓ч啱(y墨)鍥戝拰瑕佹眰渚�(l谩i)瑕�(gu墨)鑼冨悎鐞嗙殑浣跨敤鐩搁棞(gu膩n)钘ュ搧銆� 瑭虫儏
鍗氭€濇竻锛堥樋绔嬪搶鍞戝彛宕╃墖锛夌蹇岋細宸茬煡灏�(du矛)鏈棩鍝侀亷(gu貌)鏁忕殑鎮ｈ€呯鐢�銆傚湪娌荤檪鏈熼枔鎮ｈ€呰瀵嗗垏闂�(gu膩n)娉ㄦ偅鑰呯殑鐢ㄨ棩鍙嶆噳(y墨ng)鍜岀梾鎯呰畩鍖�锛屽鍑虹従(xi脿n)涓嶉仼鐧ョ媭鎳�(y墨ng)鍙婃檪(sh铆)灏遍啱(y墨)锛屾牴鎿�(j霉)閱�(y墨)鐢熺殑寤鸿鍚堢悊绶╄В鐥呮儏銆� 瑭虫儏
闃跨編瀵э紙闃挎垐缇庢媺姹€鐗囷級绂佸繉锛氫箼鑲濈梾姣掓敎甯惰€�/鎮ｈ€�銆佷笝鑲濈梾姣掓敎甯惰€�/鎮ｈ€�銆佽倽鍔熻兘鎼嶅鎮ｈ€咃紙鍗宠倽纭寲鎴栨椿鍕�(d貌ng)鎬ц倽鐥呮偅鑰咃級绂佺敤锛堝弮瑕�(ji脿n)[鐢ㄦ硶鐢ㄩ噺]鍜孾娉ㄦ剰浜嬮爡(xi脿ng)]锛夈€傛姂閮佺櫏绛夌簿绁炲績鐞嗙柧鐥呯殑娌荤檪闇€瑕佺簿纰虹殑瑷烘柗鍜屽€�(g猫)鎬у寲鐨勭敤钘ユ柟妗�锛屾偅鑰呬笉鎳�(y墨ng)鑷姹哄畾浣跨敤鍝ó钘ョ墿鎴栭毃鎰忔洿鏀圭敤钘ュ姂閲忥紝浠ュ厤寮曠櫦(f膩)涓嶅繀瑕佺殑棰�(f膿ng)闅�(xi菐n)鎴栧姞閲嶇櫏鐙€銆� 瑭虫儏
蹇冮仈(d谩)鎮咃紙姘捍閰镐紡纭タ姹€鐗囷級绂佸繉:灏�(du矛)鏈棩鍝佺殑娲绘€ф垚鍒嗘垨浠讳竴杓旀枡閬�(gu貌)鏁忕殑鎮ｈ€呯鐢�銆傜姝㈣垏闈為伕鎿囨€у柈鑳烘哀鍖栭叾鎶戝埗鍔戯紙MAOIs锛夋垨閬告搰鎬у柈鑳烘哀鍖栭叾A(MAO-A)鎶戝埗鍔戣伅(li谩n)鐢紙鍙冭(ji脿n)[钘ョ墿鐩镐簰浣滅敤]锛�銆傛湇鐢ㄩ亷(gu貌)绋嬩腑锛屾偅鑰呮噳(y墨ng)瀵嗗垏闂�(gu膩n)娉ㄨ嚜宸辩殑韬珨鍙嶆噳(y墨ng)锛屽鍑虹従(xi脿n)涓嶉仼鎴栫暟甯哥櫏鐙€锛屾噳(y墨ng)鍙婃檪(sh铆)灏遍啱(y墨)鍜ㄨ锛屾寜鐓ч啱(y墨)鐢熺殑寤鸿閰嶅悎瑾�(di脿o)鐞�锛岀洝鍙兘鍔犲揩搴峰京(f霉)閫�(j矛n)搴�銆� 瑭虫儏
鎬濈憺搴凤紙瀵岄Μ閰稿柟纭钩鐗囷級鐭湡灏�(du矛)鐓ц│椹�(y脿n)涓墍鍫�(b脿o)鍛婄殑鏈€甯歌(ji脿n)鍜屾渶椤憲鐨勪笉鑹簨浠剁偤锛氬洶鍊︼紙17.5锛咃級锛岄牠鏆堬紙10锛咃級锛屼究绉橈紙9锛咃級锛岄珨浣嶆€т綆琛€澹擄紙7锛咃級锛屽彛骞诧紙7锛咃級锛屼互鍙婅倽閰剁暟甯革紙6锛咃級?锛涢閭�?y墨ng)绌嶆サ閰嶅悎閱�(y墨)鐢熺殑娌荤檪鏂规锛屽悓鏅�(sh铆)鍔犲挤(qi谩ng)鑸囧浜烘湅鍙嬬殑婧濋€氫氦娴�锛屽煿椁�(y菐ng)鑸堣叮鎰�(脿i)濂斤紝閬╃暥(d膩ng)閫�(j矛n)琛岄珨鑲查崨鐓�锛屼互淇冮€�(j矛n)鐥呮儏鐨勫悍寰�(f霉)鍜屾彁楂樼敓娲昏唱(zh矛)閲�銆� 瑭虫儏
宸︽礇寰�(f霉)锛堥菇閰歌垗鏇叉灄鐗囷級绂佸繉锛氭湰钘ュ搧绂佺敤浜庡皪(du矛)鑸嶆洸鏋楅亷(gu貌)鏁忚€呫€傝垗鏇叉灄绂佹鑸囧柈鑳烘哀鍖栭叾鎶戝埗鍔戯紙MAOI s锛夊悎鐢紙鍙冭(ji脿n)[钘ョ墿鐩镐簰浣滅敤]锛�銆傝垗鏇叉灄绂佹鑸囧尮鑾綂鐗瑰悎鐢紙鍙冭(ji脿n)[钘ョ墿鐩镐簰浣滅敤]锛�銆傛偅鑰呮噳(y墨ng)浠旂窗(x矛)闁辫畝瑾�(shu艒)鏄庢浉(sh奴)銆佹寜瑕�(gu墨)瀹氱敤閲忔搷浣�锛屽苟闂�(gu膩n)娉ㄦ姂閮佺櫏鐨勭梾鍥犲拰闋�(y霉)闃层€傚悓鏅�(sh铆)锛岄伕鎿囨瑕�(gu墨)钘ュ簵濡傜泭钘ュ悍寰锋▊(l猫)澶ц棩鎴胯臣(g貌u)璨疯棩鍝�锛屽苟閬靛惊閱�(y墨)鐢熺殑寤鸿閫�(j矛n)琛屾不鐧傚拰搴峰京(f霉)銆� 瑭虫儏
渚�(l谩i)澹櫘锛堣崏閰歌壘鍙歌タ閰炴櫘铇墖锛変笉鑹弽鎳�(y墨ng)澶氱櫦(f膩)鐢熷湪闁�(k膩i)濮嬫不鐧傜殑绗�1-2鍛�锛屾寔绾�(x霉)娌荤檪鍚庝笉鑹弽鎳�(y墨ng)鐨勫毚(y谩n)閲嶇▼搴﹀拰鐧�(f膩)鐢熺巼閮芥渻(hu矛)闄嶄綆銆傚钩鏅�(sh铆)鎮ｈ€呭彲浠ラ伕鎿囬仼鍚堣嚜宸辩殑閬�(y霉n)鍕�(d貌ng)鏂瑰紡锛屽鏁ｆ銆佺憸浼姐€佹父娉崇瓑锛屽苟閫愭几澧炲姞閬�(y霉n)鍕�(d貌ng)寮�(qi谩ng)搴﹀拰鏅�(sh铆)闁�銆備絾闇€娉ㄦ剰锛岄亱(y霉n)鍕�(d貌ng)鏅�(sh铆)鎳�(y墨ng)閬垮厤閬�(gu貌)搴﹀嫗绱紝浠ュ厤灏�(du矛)韬珨閫犳垚璨�(f霉)鎿�(d膩n)銆� 瑭虫儏
鍟熺董锛堝瘜棣吀鍠圭～骞崇墖锛夎棩鐞嗘瘨鐞嗭細鍠圭～骞充綔鐢ㄦ(j墨)鐞嗗皻涓嶆槑纰�锛屽彲鑳芥槸閫氶亷(gu貌)鎷姉涓D2鍙楅珨鍜�5-HT2A鍙楅珨渚�(l谩i)鐧�(f膩)鎻叾鎶楃簿绁炲垎瑁傜櫏浣滅敤鍜岄洐鐩告儏鎰熼殰绀欑殑鎯呯窉绌�(w臎n)瀹氫綔鐢�?锛涢鍜磋瘻顠氱洘骞＜r(sh铆)锛屾噳(y墨ng)鍤�(y谩n)鏍奸伒閱�(y墨)鍥戠敤钘�锛屾敞鎰忚棩鐗╁彲鑳界敘(ch菐n)鐢熺殑鍓綔鐢ㄥ拰渚濊炒鎬у晱(w猫n)椤岋紝骞跺畾鏈熼€�(j矛n)琛屾鏌ヤ互纰轰繚鐢ㄨ棩瀹夊叏锛屽鏈変换浣曠枒鍟�(w猫n)鎴栦笉閬�锛屾噳(y墨ng)鍙婃檪(sh铆)灏遍啱(y墨)鍜ㄨ銆� 瑭虫儏
鍟熺董锛堝瘜棣吀鍠圭～骞崇墖锛夎棩鐗╅亷(gu貌)閲忓皫(d菐o)鑷碤T闁撴湡寤堕暦(zh菐ng)銆佺櫜鐧囩櫦(f膩)浣�銆佺櫜鐧囨寔绾�(x霉)鐙€鎱�(t脿i)銆佹┇绱嬭倢婧惰В銆佸懠鍚告姂鍒躲€佸翱娼寸暀銆佹剰璀�(sh铆)妯＄硦銆佽濡勫拰/鎴栨尟鎼�銆佹槒杩峰拰姝讳骸銆備换浣曡棩鐗╃殑閬�(gu貌)閲忎娇鐢ㄩ兘鍙兘甯朵締(l谩i)涓嶈壇鍚庢灉锛屽洜姝ゆ偅鑰呮噳(y墨ng)鐣�(d膩ng)鍦ㄩ啱(y墨)鐢熺殑鎸囧皫(d菐o)涓嬩娇鐢ㄦ甯歌寖鍦嶇殑鍔戦噺锛岃€愬績鍋氬ソ鍏烽珨鐨勭敤钘ュ伐浣�銆� 瑭虫儏
鍥犻樋绔嬪搶鍞戝彛宕╃墖鍏锋湁伪1 -鑵庝笂鑵虹礌鑳藉彈楂旂殑鎷姉浣滅敤锛屽彲鑳藉紩璧烽珨浣嶆€т綆琛€澹�?锛涢鍙╂湪鍞鎯呮硜涓嶅悓锛屽壇浣滅敤琛ㄧ従(xi脿n)绋嬪害涓嶅悓锛屾不鐧傜殑鏂规硶涔熷苟涓嶄竴妯�锛屾墍浠ユ噳(y墨ng)瑭茶鑰冩叜鎸夌収閱�(y墨)鐢熺殑瑕�(gu墨)瀹氫締(l谩i)浣跨敤钘ョ墿锛屽悓鏅�(sh铆)涔熸噳(y墨ng)瑭茶娉ㄦ剰闁辫畝钘ュ搧鐨勮(shu艒)鏄庢浉(sh奴)鍏�(n猫i)瀹�銆� 瑭虫儏
鍙湁鐣�(d膩ng)濡婂鏈熷│濂虫湇钘ョ殑鐩婅檿鏄庨’澶т簬钘ョ墿灏�(du矛)鑳庡厭鐨勬經鍦ㄩⅷ(f膿ng)闅�(xi菐n)鏅�(sh铆)锛屾柟鍙湇宸︽礇寰�(f霉)銆傛姂閮佺櫏鍦ㄤ腑鍦�(gu贸)鐨勭櫦(f膩)鐥呯巼姣旇純楂�锛屼絾鏄敱浜庡眳姘戠己涔忓皪(du矛)鍏剁殑瑾�(r猫n)璀�(sh铆)鍜屼簡瑙�锛屾墍浠ュ氨鍙兘鏈�(hu矛)瀛樺湪涓嶈兘鏃╂湡鎺ュ彈娌荤檪鐨勭従(xi脿n)璞°€� 瑭虫儏
澶у闇€瑕佹纰轰娇鐢ㄨ棩鐗�锛屾皑纾哄繀鍒╃墖鐢ㄦ硶鐢ㄩ噺鏄€氬父鎯呮硜涓�锛岃嫢姣忓ぉ鍔戦噺灏忎簬鎴栫瓑浜�400mg锛屾噳(y墨ng)涓€娆℃湇瀹�锛岃嫢姣忓ぉ鍔戦噺瓒呴亷(gu貌)400mg锛屾噳(y墨ng)鍒嗙偤鍏╂鏈嶇敤銆傛澶�锛屽畾鏈熷京(f霉)鏌ュ拰瀵嗗垏闂�(gu膩n)娉ㄨ棩鐗╁壇浣滅敤涔熸槸姣旇純閲嶈鐨�锛屾偅鑰呭強瀹跺爆鎳�(y墨ng)瀹氭湡鑸囬啱(y墨)鐢熸簼閫�锛屽強鏅�(sh铆)鍙嶉鐥呮儏璁婂寲锛屼互渚胯(di脿o)鏁寸敤钘ユ柟妗�銆� 瑭虫儏
纰抽吀閶扮珐閲嬬墖鍦ㄤ娇鐢ㄦ檪(sh铆)鏈変竴瀹氱殑闄愬埗姊濅欢锛岄儴鍒嗕汉缇や笉瀹滀娇鐢ㄦ垨闇€瑕佽(j菒n)鎱庨伕鎿�銆傜⒊閰搁嫲绶╅噵鐗囩蹇屾槸鑵庡姛鑳戒笉鍏ㄨ€�銆佸毚(y谩n)閲嶅績鑷熺柧鐥呮偅鑰呯鐢ㄣ€傚洜姝�锛屽湪钘ョ墿绂佸繉鑼冨湇涔嬪収(n猫i)鐨勪汉缇�锛屽垏蹇岀洸鐩娇鐢ㄨ┎钘ョ墿銆� 瑭虫儏
纰抽吀閶扮珐閲嬬墖甯歌(ji脿n)涓嶈壇鍙嶆噳(y墨ng)鍙ｅ共銆佺叐娓�銆佸椋�銆佸灏裤€佷究绉�銆佽吂鐎�銆佹儭蹇�銆佸様鍚�銆佷笂鑵圭棝銆傚缓璀拌簛鐙傜櫏鐨勬偅鑰呰绌嶆サ鐨勯厤鍚堥啱(y墨)甯敤钘ヤ娇鐢ㄨ棩鐗�锛岃(di脿o)鐞嗚韩楂旀湡闁撹椁�(y菐ng)鎴愬ソ鐨勭敓娲荤繏(x铆)鎱ｏ紝瑕佹敞鎰忎笉鑳介亷(gu貌)澶氱殑鍕炵疮锛岃€屼笖閭勮澶氬仛涓€浜涢珨鑲查崨鐓夛紝閫欐ǎ鍙互娓涘皯鐤剧梾鐨勭櫦(f膩)鐢�銆� 瑭虫儏
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姝ｅ搧淇濋殰 鏀惧績閬歌臣(g貌u)
鐢ㄨ棩鍏ㄧ▼鎸囧皫(d菐o)
寤犲鎺堟瑠(qu谩n) 姝ｅ搧娓犻亾
瀹夊叏鏀惧績 闅辩閰嶉€�
